Cancer treatment has traditionally focused on eliminating malignant cells through chemotherapy, radiation, and targeted therapies. However, a groundbreaking approach developed by researchers at KAIST, known as BENEIN (Boolean Network Inference and Control) , presents an innovative way to combat cancer. Instead of destroying cancer cells, BENEIN focuses on reprogramming them back to their normal state by controlling cellular differentiation pathways. What is BENEIN? BENEIN is a computational framework that leverages Boolean network modeling and single-cell transcriptome data to analyze and control gene regulatory networks. It identifies key master regulators —genes responsible for cell differentiation—and manipulates them to reverse cancerous transformations in cells. How Does BENEIN Work? Data-Driven Analysis : BENEIN uses single-cell transcriptome data to map out cellular differentiation trajectories. Boolean Network Modeling : It applies a mathematical approach to simulate ...